I really like pokerstudent's line of thought here. "Instinct" and experience really only help you to gain a read on the other players, what cards they might be holding, how they likely they are to fold or call in certain situations, etc. But you have to know what to do with that information. Even if you're playing with a marked deck and could read people's minds, you still have to understand pot odds, EV, and perhaps "dynamical value" in order to maximize your profit. Right?

Pokerstudent, I really don't know how to answer your questions, but let me know what you come up with.