If I have A10 and I raise $1 PF in position, and villain calls, flop is K J 8 rainbow, no way am I cbetting that flop
You have to consider that while villain may indeed be holding a hand with a mix of middling/paint cards. But, he could be holding A-x, or a PP. Both of those hands he will fold to a continuation bet on the flop. In poker, there are no absolutes. So never c-betting this flop will be a surefire way to miss out on some value.

Now same scenario and flop is 5 8 3 I definitely cbet, even OOP I might make it a PSB
C-betting is almost always good. I wish i knew the exact source but i know that your opponent is only going to make a pair 33% of the time on any given flop.

Anyways, with this particular hand you should not generally lead out with a much bigger bet than on a more "threatening" looking board. Your c-bets should tend to look the same on any given flop - as well as those c-bets with very strong hands - since that way your opponents will not be able to tell when you are bluffing and when you are not. There is still a good chunk of your opponents range that missed this flop. K-10, A-9, etc. that will still fold this flop whether or not you bet 1/2PSB or the full pot (whether or not this discourages them from bluffing would make for an interesting discussion). But, you lose more when pocket pairs that are bigger than the board or those that flop sets call or raise your large flop bet.

Basically, while both flops look different, they only help your opponents hole cards slightly more often with the K-J-8rainbow flop. Therefore, there is little reason to drastically alter the size of your flop bets on the texture of the board, particularily when facing a single opponent.