as you saw from the sweat hoopy , 25nl will mean that you automatically end up 3 betting more. It is "the game" at that level and people have a better understanding of when they should be calling and folding to 3bets. At 10nl theres nothing like that knowledge and you could end up spewing large amounts of money against people who can't fold.
steal stats and 3bet stast on your HUD will help you.