I stepped up to 25nl this week with a $200 br, dropping back down at $150 (currently $260), I'm sick of being a nit with my br, I've been stuck at 10nl for what seems like an eternity, and I tend to blow my cash game profits from 10nl quickly on mtts. Standard isn't much better at 25nl, there's still plenty of idiots about, one guy I bumhunt runs at 85/8 and calls down any piece of the flop.
Don't be afraid to step up, and don't be too proud to step back down.