I wouldn't loosen up too much pf.

Remember what got you there in the first place. Don't be so quick to give it back.

Also keep two things in mind:

Because you are the big stack, people will look you up to get some of that stack if they have a piece of the flop.

Because you have the big stack, people will stay away from you because they don't want to get tangled up with you without some kind of hand. You have a little more FE....

All this goes out the window if they are shorties.