so in general what am i looking out for preflop with a relatively low pair where I should not see the flop?

ie what kind of betting would tell me that i should not see, say a 3xBB preflop bet, even if there are 2-3 people going to the flop ?

also, how can you be certain that others will see the flop if you're say only the 2nd person to call (say UTG+2 puts in 30c (10c BB)) - would i call that with 22 or 55 ?