I don't think he actually meant loosen up as in playing marginal hands, but just changing gears like trying to get in cheap with mid suited connectors in late position when you (if your that type) would normally throw them away, I think that is what he means.

When I get a long period of cold cards and I am playing online I just go do something else if I already have a general feel of how the people at my table play. That way you aren't staring at the screen panicking when you should be patient.

If you feel that you are being blinded away because you can't even raise or call a hand due to cold cards, get up, go walk around your place grab a drink, breathe then come back and start kicking butt.