I'd call the reraise and try for a reasonable showdown. (Half pot or so, espeically since I'm now playing only one card on the river).
I don't think 2 pair is good enough to go broke with in an unraised pot. If villian has any reason at all, I'd expect to see 22 (or, remotely, 77, AK). Like nutsinho said, I don't like my hand with this much action out of nowhere.