I think a whale utg opening range is fairly likely to cold call your 4-bet so I don't mind it. It also has the benefit of punishing the CO reg for over-isoing the whale (if he is). I've seen people 4bet bluff a shitload in your spot for this reason and it has made me tempted to stack off quite light vs those 4-bets.
As for 4-bet folding, I'd get this in, you have QQ and 20% of your stack in. The donk will sweeten the pot quite nicely with his stackoff range and you'll often be in great shape 3 way vs the reg's AK and whale's ace whatever. I also think the reg could probably play JJ in this way. I wouldn't be surprised if this is a shove even if reg can only have QQ+ AK, though (which he certainly can have all of, no way in hell he folds AK).
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