It all depends, a line I've taken recently that works pretty well is to just call the c-bet and lead the turn for 2/3 pot. Most players don't have the balls to try and make a move on you there since it might get expensive. Usually I'll check-call two bets at most if I have a very marginal hand like second pair that I think might be good. If they fire three times usually I'll just give them credit for a hand unless I've got a monster read.