I decided to post this in the high stakes section since I thought it was maybe a little more relevant here.

Say I raise preflop with some hand and an opponent calls. Flop comes 3 rags with a flush draw which doesn't help my hand. Opponent checks, I bet, and opponent calls immediately, which suppose from previous hands I know usually indicates a draw. No obvious draws complete on the turn, but the question is, should you continue bluffing? The problem seems to be you expect your opponent to be willing to call reasonably-sized bets, and you risk losing a large pot if your opponent hits, or if you're wrong and your opponent has a made hand. Also a river bluff loses legitimacy if you check behind on the turn, and may get called from a wide range of hands, even if your opponent misses his primary draw. Should you simply give up in these situations? It obviously depends to a certain degree on the player's tendencies, but is one policy better than another in general, assuming a random opponent? Any ideas on this?