6max is different from full ring, but you don't need to go all apeshit and over defend your blinds or turn into a top pair fish and its still bad to cold call raises with KTo out of position.

You can win by playing a solid, smart game so play whatever style you're comfortable with. When you first make the transition, you will lose more money by over adjusting than by playing too tight.

There are a few adjustments and you will run into more pots with those annoying tough regulars but you will also run into more pots with the fishtards at the table.