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I run 16/11 at 25NL/50NL with fairly respectable winrates... 4PTBB/100 on average.
I'm curious if any of the "must be 2% gap" types have ever done a winrate analysis comparing the two styles.
Basically the only difference between me and a 13/11 is that I still open limp low PPs from all positions. I kind of question how much that should affect my winrate given that most critical decisions, where the most money is won & lost is postflop, so a little bit of preflop loose passivity shouldn't do TOO much to your winrate if you're solid postflop. Sure I get burned occasionally & waste a BB when there's 3-betting behind or a PFR from a shortie, so maybe the limp is closer to neutral EV than a limp from LP behind other limpers.
Spoon also made the point that the more passive style is more of an exploitable style, which I imagine is a more important point as you go up in the limits and find yourself against smarter opponents, which is maybe why it's the 100NL+ types who are running 2% gaps & us microstakers are running larger gaps.
Or maybe it's because the 100NL+ types are true sharks, and we're still sharks on training wheels 
I know when I run into a 15/4 I certainly play differently than vs a 15/12. It's far easier to get away from a raise made by a 15/4 than it is a 15/12, so anyone running a HUD (and correctly interpreting stats) will be able to exploit the more transparent style of play that the large gap suggests.
...then again, the HUD multi-tabling regs are usually nitty & hard to extract from at microstakes, so maybe it doesn't matter THAT much...
In conclusion: I don't f'n know
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