Villain is 54/37 tard with 21% 3bet and I've never seen him not iso when given opportunity (smallish sample).

No-Limit Hold'em, $4.00 BB (6 handed) - Hold'em Manager Converter Tool from FlopTurnRiver.com
SB ($265.47)
BB ($611.26)
UTG ($103.18)
MP ($83.62)
Hero (CO) ($410)
Button ($506)

Preflop: Hero is CO with K, A
UTG calls $4, 1 fold, Hero calls $4, Button bets $20, 3 folds, Hero raises $80, Button calls $64

Flop: ($178) 10, 8, 4 (2 players)
Hero checks, Button bets $45, Hero calls $45

Turn: ($268) 3 (2 players)
Hero checks, Button bets $90, Hero calls $90

River: ($448) 10 (2 players)
Hero checks, Button bets $287 (All-In), Hero calls $191 (All-In)

Any other way to play this hand postflop?