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Like mentioned your image is certainly very important, with a loose image you can't make big lay downs as people will play back at you with weak holdings. Say just a big overpair, on a drawheavy flop I would very rarely fold to an all in only 100bb deep, if I run into a set or two pair, too bad. Again this depends on your opponents image too though.
One advantage with 3-betting a wide range preflop in my opinion, is that you don't have to make these big laydowns. That's a huge leak I had when I was playing 400/600NL, I would only 3-bet AA/KK/QQ/AK preflop. Thinking players figured this out of course and only called me with pp and either folded flop or stacked me with a set. When playing tight however, you have to be able to make these tough laydowns, I don't really have much experience playing tight but I would think it would be quite difficult finding the right spots to make these big laydows in.
I believe making smaller laydowns might be more important however, figuring out when to call, fold, value bet or bluff with those standard ~20bb bets on the river makes up for a lot money long term. I've noticed that in tough 10/20 games that I just bleed chips this way slowly cause I'm not making good enough decisions here, and that kinda sucks.
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