I've been in this situation a couple of times last week at 10NL/20NL:
4-6 players limp, or there's a minraise and a couple of calls, and I'm in the bb with AQo, AJs, KQs.
It takes a 15-20bb raise to get less than 4 people to the flop.
My options are: make the overraise and stack off with TPGK, otherwise give up. Or: Pop it up, get everyone to call and continue with caution.
Or even just check it - which I actually do with 99, ATs.
To complicate things, often enough I'm 200-400bb deep, and there's another big stack at the table who might be tempted to setmine against me here.

Let's take an almost best-case scenario where I have :Ah::Jh:, I make it 15bb to go against 5 limpers, and get 2 calls, and the flop is something like :Js:.
This hits their range hard, and I have to bet it hard, and stack off to a reraise.
Now if I'm 200 deep, and another player has me covered this can become ugly. If I bet out full pot, then there's almost 100bb in the pot, and an overshove for 150bb effective is really tough, and does happen.
So I'm really kind of lost here, if the situation just sucks but is still profitable, or if I should just curse the poker gods for giving me good hand in the blinds, and play a multi-way pot like a nit.