Sure. The key word is sparingly. Light 4-betting is high risk/low reward because you're usually committing yourself to call a 5-bet shove. So if you don't love variance, a better way of dealing with a guy that's 3-betting you constantly is to leave the table. If you are going to 4-bet light (which I define as a wider range than QQ+/AK) then you have 3 options.

1. Raise smaller than pot. With 100bb stacks, a less than pot-sized raise usually makes it correct to fold to a 5-bet push, if you think villain's only pushing QQ+/AK. Pros: Less variance. 4-betting and folding to a push might get your "real" 4-bets more action. Cons: Light 3-betting villains often 5-bet push wider than QQ+/AK. A small 4-bet probably has less fold equity than a larger one. You look like a nit.

2. Raise pot or more. With 100bb stacks, a pot-sized raise or more usually makes it correct to call a 5-bet push, as long as villain's range includes AK. Pros: Probably more FE than a smaller 4-bet. Great for metagame when you call a 5-bet push with 22 or 65s. Cons: You're always getting your money in with the worst of it when you call a 5-bet push. More variance.

3. 4-bet push. Pro: Most fold equity? Con: Always behind when called.

I usually go with option #2, but with a specific read (3-bets light but is a nit about stacking off) I'll go with #1. I almost never 4-bet push light, if anyone likes to do I'm curious to hear why/when.

Before I 4-bet light with a pocket pair I like to be sure that villain will felt AK pre-flop. If he won't, pocket pairs are huge dogs and should just be folded to 3-bets oop. (Calling and c/r'ing any flop AI is an option too, but I prefer to make that bluff in position.) In the games I play (2/4 & 3/6 at FT) most regulars will felt AK pre-flop, so it's not a problem. Before I 4-bet light with AQ or AJ, I want to be sure that villain will felt JJ (and preferably TT too) pre-flop, because these hands don't do well at all vs. QQ+/AK. Again, most opponents in the games I play do felt JJ. 4-betting light with low suited connectors (98s->65s) or suited aces doesn't depend too much on villain's range, because they fare equally well against most 5-bet pushing ranges. Still, they don't do as well as any pp does against QQ+/AK or as well as AQ does vs. TT+/AK. But, they do well enough to call a 5-bet push if you're getting over ~2.2:1, and they're awesome for metagame.

Comments, questions, corrections welcome.