You'll be playing lots of 4 handed aswell, just play pratically as if first two have folded at 6m (you could argue about cards-bunching though I don't think this is very relevant here).
Just try and figure out how to play vs the players / tables most optimally... I think the fact there's one less seat makes little difference. More importantly will be playing wrt table/player conditions.
Ive just finished 100k hands at the 200nl 5m so if youre gonna be at these tables then hit me up if you want.