This is where my post in the beginner forum comes in.

If this guy folds a lot of flops, I'll isolate with almost ATC because my value comes from c-betting almost all flops and him folding a lot. I'm happy to raise a touch more v's this guy PF also to build the pot.

If this guy is a station postflop, then I isolate with any two cards T or higher, dont c-bet as much as normal (v's some guys hardly at all) if I miss, but value bet fairly large any pair I hit. I'm happy to raise this slightly lower PF if its still likely to isolate him, since my value comes from value betting postflop, so risk the minimum when I miss.

Thats obvious with fairly extreme cases, and the rest of the table matters.