mix-its definitely a feel thing, and don't be afraid to be wrong. the best players all go with their gut very frequently. Yesterday i 4bet to 22bb and called off 78 more with AJo and was miles ahead vs. a reg with whom i had hardly any history to speak of- i just subconsciously analyzed his timing and snapcalled. sometimes they turn over the supernuts in these situations, you lose confidence in yourself, and you make a mental note to not spew so hard in the future, but in reality you probably didn't make much of a mistake vs. their range if any. if you don't trust your brain to make sublime reads and are unwilling to battle in thin spots you will never be a great player.