If I understand correctly, indifference isn't necessarily about making villain not be able to bluff any two cards, because there will be spots postflop where any two card bluffs are profitable, particularly on weird board run outs which are infrequent. As long as your preflop strategy doesn't have any holes in it, you will deny villain the opportunity to play any two cards because if you defend appropriately you will be realizing enough equity to make him just bet/bet/betting a lot a losing strategy.
Regarding the idea of having spots where you'll fold more than the alpha number states in practice, I have made a cREV tree proof for a simplified river scenario. If you're interested in looking over it message me on Skype and I'll send you the output.
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