Am I misunderstanding you?
You think that in this spot, Villain's range is massively dominated by Hero's range, and you want Villain to stop putting money in the pot?
That should not be a reason to do anything to make Villain fold, in general.
That should be exactly the time to make Villain feel like his (transparent) bluff (attempt) will work.
EDIT: So Villain x/f OTT. How much money did Hero win/lose by giving him the opportunity to make a low equity bluff attempt?